Aflatoxins are a group of highly toxic secondary metabolites, with B1, B2, G1, and G2 being the primary types, among which Aflatoxin B1 exhibits the highest toxicity. Primarily produced by the fungal species such as Aspergillus flavus and Aspergillus parasiticus, they frequently contaminate susceptible agricultural commodities such as corn, peanuts, legumes, and tree nuts. Exposure to these toxins can lead to hepatotoxicity, immunosuppression, and hepatocellular carcinoma. Notably, Aflatoxin B1 is recognized as one of the most potent naturally occurring carcinogens known.
The column operates on the principle of specific antigen-antibody binding. High-affinity antibodies against aflatoxins B1, B2, G1 and G2 are covalently immobilized on the gel medium. As the sample extract passes through the column, the antibodies selectively capture the aflatoxins, forming a stable complex, while interfering matrix components are removed during the washing step. Finally, the antigen-antibody complex is disrupted using methanol, eluting the aflatoxins to yield a highly purified sample ready for subsequent HPLC or LC-MS/MS analysis.
Instruction Manual-Elaboric-The SEPurast IAC for Aflatoxins B1,B2,G1 and G2.pdf
Matrix: Food, oil, nut, feed, herbs, tea, etc.
Volume: 1mL / 3mL
Test: 25T / 50T
Storage: 2–8 ℃
Shelf Life: 18 months